Hong-Zin Lee Selected Research

6- (N,N- dimethylamino)- 2- (naphthalene- 1- yl)- 4- quinazolinone

5/2013

A novel antitubulin agent, DPQZ, induces cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.

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Hong-Zin Lee Research Topics

Disease

20	Neoplasms (Cancer) 01/2019 - 03/2006
11	Prostatic Neoplasms (Prostate Cancer) 02/2016 - 11/2009
9	Lung Neoplasms (Lung Cancer) 01/2019 - 03/2005
6	Mouth Neoplasms (Oral Cancer) 01/2019 - 12/2009
6	Carcinoma (Carcinomatosis) 09/2012 - 08/2003
4	Inflammation (Inflammations) 07/2019 - 04/2013
3	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2015
3	Colorectal Neoplasms (Colorectal Cancer) 09/2013 - 01/2013
3	Margins of Excision 07/2013 - 09/2010
3	Lymphatic Metastasis 07/2013 - 09/2010
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/2011 - 01/2005
2	Hyperglycemia 07/2019 - 03/2004
2	Neoplasm Metastasis (Metastasis) 01/2013 - 01/2010
1	Infections 01/2022
1	COVID-19 01/2022
1	Periodontitis 07/2019
1	Periodontal Diseases (Periodontal Disease) 07/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Starvation 01/2019
1	Fibrosis (Cirrhosis) 01/2015
1	Thalassemia 07/2014
1	Iron Overload 07/2014
1	7 Hereditary Prostate Cancer 07/2013
1	Respiratory Hypersensitivity 04/2013
1	Disease Progression 04/2013
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2013
1	Sarcoma (Soft Tissue Sarcoma) 09/2012
1	Genomic Instability 09/2012

Drug/Important Bio-Agent (IBA)

6	aloe emodinIBA 09/2012 - 08/2003
5	Biomarkers (Surrogate Marker)IBA 02/2016 - 10/2011
4	Proteins (Proteins, Gene)FDA Link 01/2019 - 03/2005
4	AndrogensIBA 11/2013 - 02/2011
4	Prostate-Specific Antigen (Semenogelase)IBA 07/2013 - 11/2009
3	DNA (Deoxyribonucleic Acid)IBA 09/2012 - 01/2005
3	LuteolinIBA 09/2010 - 01/2005
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2019 - 07/2006
2	AntioxidantsIBA 07/2019 - 03/2006
2	Glucose (Dextrose)FDA LinkGeneric 07/2019 - 03/2004
2	Pharmaceutical PreparationsIBA 01/2019 - 05/2013
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2019 - 01/2019
2	CytokinesIBA 10/2016 - 09/2013
2	NF-kappa B (NF-kB)IBA 10/2016 - 11/2013
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2016 - 04/2010
2	MicroRNAs (MicroRNA)IBA 12/2014 - 02/2011
2	Carcinoembryonic AntigenIBA 09/2013 - 01/2013
2	rottlerinIBA 09/2012 - 01/2011
2	Photosensitizing Agents (Photosensitizers)IBA 09/2012 - 12/2010
2	Codon (Codons)IBA 09/2012 - 12/2011
2	beta CateninIBA 01/2010 - 12/2009
1	ceftobiproleIBA 01/2022
1	MelatoninIBA 01/2022
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 07/2019
1	LipopolysaccharidesIBA 07/2019
1	Therapeutic UsesIBA 07/2019
1	Orlistat (Xenical)FDA Link 01/2019
1	Fenofibrate (CiL)FDA LinkGeneric 01/2019
1	nemonoxacinIBA 01/2019
1	Cyclin EIBA 01/2019
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2019
1	PalmitatesIBA 01/2019
1	Cyclin DIBA 01/2019
1	CaspasesIBA 01/2019
1	Levofloxacin (Levaquin)FDA Link 01/2019
1	LipidsIBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2016
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2016
1	Oxygen (Dioxygen)IBA 01/2015
1	trigonellineIBA 01/2015
1	Coffee FDA Link 01/2015
1	NaphthoquinonesIBA 01/2015
1	Vitamin K 3 (Menadione)FDA Link 01/2015
1	DeferiproneIBA 07/2014
1	Isoflurophate (DFP)FDA Link 07/2014
1	Deferasirox FDA Link 07/2014
1	Transcription Factors (Transcription Factor)IBA 11/2013
1	Interleukin-10 (Interleukin 10)IBA 09/2013
1	Insulin (Novolin)FDA Link 07/2013
1	6- (N,N- dimethylamino)- 2- (naphthalene- 1- yl)- 4- quinazolinoneIBA 05/2013
1	PhosphatidylserinesIBA 05/2013
1	Phosphotransferases (Kinase)IBA 05/2013
1	OvalbuminIBA 04/2013
1	AllergensIBA 04/2013
1	Calcitriol Receptors (Calcitriol Receptor)IBA 04/2013
1	methyl 4-azidophenylacetimidate (APAI)IBA 04/2013
1	Peptide Hydrolases (Proteases)FDA Link 01/2013
1	Matrix Metalloproteinases (MMPs)IBA 01/2013
1	CateninsIBA 01/2013
1	HSP27 Heat-Shock ProteinsIBA 09/2012
1	8-hydroxyguanineIBA 09/2012
1	Focal Adhesion Protein-Tyrosine KinasesIBA 09/2012
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 09/2012
1	Protein Kinase C-deltaIBA 09/2012
1	TubulinIBA 09/2012
1	ActininIBA 09/2012
1	Methanol (Carbinol)IBA 01/2012

Therapy/Procedure

8	Prostatectomy (Retropubic Prostatectomy) 01/2016 - 11/2009
7	Therapeutics 12/2014 - 02/2011
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 10/2016 - 06/2011
2	Photochemotherapy (Photodynamic Therapy) 09/2012 - 08/2011
1	Lasers (Laser) 07/2019